Paper published! GWAS of Hernias.
Hernias are characterized by protrusion of an organ or tissue through its surrounding cavity and often requires surgery.
We performed genome-wide association study (GWAS) scans on 65,492 cases of five different types of hernia and two combined groups against controls without a history of any hernia in UK Biobank data. The initial findings for inguinal hernia were followed up in 23,803 additional cases in cohorts from Finland, Estonia and Denmark.
Here’s a summary of the study in Danish and English.
The article “Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci” was published in Nature Communications on June 9th 2022.